Small molecules which mimic Bexarotene treatment
Canned Analysis
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General Information
AccessionDCA00012240
TitleSmall molecules which mimic Bexarotene treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Bexarotene treatment in the LIVER from Sprague Dawleys cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d688e467bea600fb8f78
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3560
Cell TypeLIVER from Sprague Dawleys
Drug NameBexarotene
DrugBank IDDB00307
Organismrat
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM89873, GSM89875, GSM89878, GSM89881
Perturbed SamplesGSM89849, GSM89852, GSM89855
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3952
Gene Expression Omnibus
Targretin, 9-cis retinoic acid, and 4-hydroxyphenylretinamide effect on various organs
63
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