Small molecules which reverse Cyclophosphamide treatment
Canned Analysis
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General Information
AccessionDCA00012277
TitleSmall molecules which reverse Cyclophosphamide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Cyclophosphamide treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d800e467bea600fb9022
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2697
Drug NameCyclophosphamide
DrugBank IDDB00531
Organismmouse
PubChem CID2907
SMILES IDC1CNP(=O)(OC1)N(CCCl)CCCl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM677900, GSM677901, GSM677902, GSM677903, GSM677904, GSM677905, GSM677906, GSM677907, GSM677908, GSM677909
Perturbed SamplesGSM677910, GSM677911, GSM677912, GSM677913, GSM677914, GSM677915, GSM677916, GSM677917, GSM677918, GSM677919
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE27440
Gene Expression Omnibus
Cyclophosphamide effect on splenocytes: time course
21
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