Small molecules which mimic Cyclophosphamide treatment
Canned Analysis
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General Information
AccessionDCA00012278
TitleSmall molecules which mimic Cyclophosphamide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cyclophosphamide treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6efe467bea600fb8fa8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2698
Drug NameCyclophosphamide
DrugBank IDDB00531
Organismmouse
PubChem CID2907
SMILES IDC1CNP(=O)(OC1)N(CCCl)CCCl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM677940, GSM677941, GSM677942, GSM677943, GSM677944, GSM677945, GSM677946, GSM677947
Perturbed SamplesGSM677948, GSM677949, GSM677950, GSM677951, GSM677952, GSM677953, GSM677954, GSM677955
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27440
Gene Expression Omnibus
Cyclophosphamide effect on splenocytes: time course
21
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