Small molecules which reverse Doxorubicin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012317
TitleSmall molecules which reverse Doxorubicin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Doxorubicin treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1db84e467bea600fb91b2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2721
Drug NameDoxorubicin
DrugBank IDDB00997
Organismhuman
PubChem CID31703
SMILES IDCC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM11707, GSM11716
Perturbed SamplesGSM11694, GSM11695
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE763
Gene Expression Omnibus
Breast cancer cell line ZR-75-1 response to chemotherapeutics: time course
28
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.