Breast cancer cell line ZR-75-1 response to chemotherapeutics: time course
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE763
TitleBreast cancer cell line ZR-75-1 response to chemotherapeutics: time course
DescriptionAnalysis of the response of luminal epithelium derived breast cancer line ZR-75-1 to either doxorubicin or 5-fluorouracil. Cells examined 12, 24, and 36 hours following treatment. Results provide insight into the response of breast cancers derived from different cell types to chemotherapeutics.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE763
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Geneset

Small molecules which mimic Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Doxorubicin treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated following Doxorubicin treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated following Doxorubicin treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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