Small molecules which reverse Isoflurane treatment
Canned Analysis
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General Information
AccessionDCA00012389
TitleSmall molecules which reverse Isoflurane treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Isoflurane treatment in the fear cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef18e467bea600fb9a50
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2771
Cell Typefear
Drug NameIsoflurane
DrugBank IDDB00753
Organismrat
PubChem CID3763
SMILES IDC(C(F)(F)F)(OC(F)F)Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM30804, GSM30805, GSM30806, GSM30807, GSM30808
Perturbed SamplesGSM30809, GSM30810, GSM30811, GSM30812, GSM30813
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1779
Gene Expression Omnibus
Anesthesia and fear conditioning effect on amygdala
14
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