Anesthesia and fear conditioning effect on amygdala
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE1779
TitleAnesthesia and fear conditioning effect on amygdala
DescriptionAnalysis of basolateral amygdalae from animals following isoflurane treatment, pain treatment, or fear conditioning alone or in combination with isoflurane treatment. Fear conditioning leads to long-term memory formation. Isoflurane is a general anesthetic and amnestic agent.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1779
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic Isoflurane treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Isoflurane treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Isoflurane treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Isoflurane treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated following Isoflurane treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated following Isoflurane treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Interaction network and enrichment analysis of genes downregulated following Isoflurane treatment
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated following Isoflurane treatment
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes downregulated following Isoflurane treatment
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated following Isoflurane treatment
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
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