Small molecules which mimic Lubiprostone treatment
Canned Analysis
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General Information
AccessionDCA00012392
TitleSmall molecules which mimic Lubiprostone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Lubiprostone treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dbb6e467bea600fb91c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2778
Drug NameLubiprostone
DrugBank IDDB01046
Organismmouse
PubChem CID656719
SMILES IDCCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM457637, GSM457639
Perturbed SamplesGSM457638, GSM457640
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE18327
Gene Expression Omnibus
Lubiprostone effect on cystic fibrosis small intestine phenotype
7
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