Small molecules which mimic Pioglitazone treatment
Canned Analysis
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General Information
AccessionDCA00012466
TitleSmall molecules which mimic Pioglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Pioglitazone treatment in the skeletal muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ecc1e467bea600fb9946
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2843
Cell Typeskeletal muscle
Drug NamePioglitazone
DrugBank IDDB01132
Organismrat
PubChem CID4829
SMILES IDCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM533026, GSM533027, GSM533028
Perturbed SamplesGSM533032, GSM533033, GSM533034
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21329
Gene Expression Omnibus
Peroxisome proliferator-activated receptor- ligand treatment: adipose tissue, skeletal muscle, and liver
42
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