Peroxisome proliferator-activated receptor- ligand treatment: adipose tissue, skeletal muscle, and liver
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE21329
TitlePeroxisome proliferator-activated receptor- ligand treatment: adipose tissue, skeletal muscle, and liver
DescriptionAnalysis of 3 tissue types from lean and insulin resistant, obese Zucker rats untreated or treated with 1 of 4 PPAR ligands (pioglitazone, rosiglitazone, troglitazone, AG035029). Results provide insight into the role of PPAR as an essential mediator for maintenance of body insulin sensitivity.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE21329
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Drug Name
Geneset

Small molecules which mimic Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Troglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Pioglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Pioglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Pioglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Pioglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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