Small molecules which reverse Cobalt dichloride hexahydrate treatment
Canned Analysis
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General Information
AccessionDCA00012625
TitleSmall molecules which reverse Cobalt dichloride hexahydrate treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Cobalt dichloride hexahydrate treatment in the H4IIEC3 liver cell line - 62uM cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d8ade467bea600fb906e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3117
Cell TypeH4IIEC3 liver cell line - 62uM
Drug NameCobalt dichloride hexahydrate
Organismrat
PubChem CID24643
SMILES IDO.O.O.O.O.O.[Cl-].[Cl-].[Co+2]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1240502, GSM1240505, GSM1240508, GSM1240511
Perturbed SamplesGSM1240504, GSM1240507, GSM1240510, GSM1240513
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE51207
Gene Expression Omnibus
Cobalt effect on liver cell line MH1C1: dose response
28
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