Cobalt effect on liver cell line MH1C1: dose response
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE51207
TitleCobalt effect on liver cell line MH1C1: dose response
DescriptionAnalysis of MH1C1 liver cells exposed to 160 or 310 uM cobalt chloride. Cobalt (Co) is a heavy metal found naturally in low concentrations and used in military and industrial applications. Co exposure can result in adverse health effects. Results provide insight into the mechanisms of Co toxicity.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51207
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Cobalt dichloride hexahydrate treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated following Cobalt dichloride hexahydrate treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated following Cobalt dichloride hexahydrate treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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