Small molecules which reverse D-serine treatment
Canned Analysis
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General Information
AccessionDCA00013037
TitleSmall molecules which reverse D-serine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by D-serine treatment in the Forebrains - Animals treated with 50mg/kg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1def3e467bea600fb9336
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3389
Cell TypeForebrains - Animals treated with 50mg/kg
Drug NameD-serine
Organismrat
PubChem CID71077
SMILES IDC(C(C(=O)O)N)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM271362, GSM271365, GSM271367, GSM271369
Perturbed SamplesGSM271386, GSM271387, GSM271388, GSM271389
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10748
Gene Expression Omnibus
D-serine effect on the brain: dose response
35
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