D-serine effect on the brain: dose response
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE10748
TitleD-serine effect on the brain: dose response
DescriptionAnalysis of forebrains of animals treated with up to 500 mg/kg D-serine for 96 hours. D-serine is involved in many physiological processes through its interaction with the glycine binding site of the NMDA receptor. Results provide insight into the impact of D-serine exposure on neuronal functions.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10748
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse D-serine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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