Small molecules which mimic Streptozocin treatment
Canned Analysis
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General Information
AccessionDCA00013108
TitleSmall molecules which mimic Streptozocin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Streptozocin treatment in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef3ce467bea600fb9a5e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3439
Cell Typeliver
Drug NameStreptozocin
DrugBank IDDB00428
Organismmouse
PubChem CID29327
SMILES IDCN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM933351, GSM933352, GSM933353, GSM933354, GSM933355, GSM933356
Perturbed SamplesGSM933357, GSM933358, GSM933359, GSM933360, GSM933361, GSM933362
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38067
Gene Expression Omnibus
Hepatic gene expression in streptozotocin-induced diabetic mice fed a quercetin diet
21
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