Small molecules which reverse Quercetin treatment
Canned Analysis
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General Information
AccessionDCA00013111
TitleSmall molecules which reverse Quercetin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Quercetin treatment in the liver (treated with streptozotocin) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ee75e467bea600fb9a08
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3440
Cell Typeliver (treated with streptozotocin)
Drug NameQuercetin
DrugBank IDDB04216
Organismmouse
SMILES IDOc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM933357, GSM933358, GSM933359, GSM933360, GSM933361, GSM933362
Perturbed SamplesGSM933363, GSM933364, GSM933365, GSM933366, GSM933367, GSM933368
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38067
Gene Expression Omnibus
Hepatic gene expression in streptozotocin-induced diabetic mice fed a quercetin diet
21
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