Small molecules which mimic Caerulein treatment
Canned Analysis
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General Information
AccessionDCA00013322
TitleSmall molecules which mimic Caerulein treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Caerulein treatment in the Livers - 48 hours after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d69be467bea600fb8f80
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3566
Cell TypeLivers - 48 hours after exposure
Drug NameCaerulein
Organismrat
PubChem CID16132921
SMILES IDCC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM127079, GSM127080, GSM127081, GSM127082, GSM127083, GSM127084, GSM127085, GSM127086, GSM127087
Perturbed SamplesGSM127054, GSM127055, GSM127056, GSM127057, GSM127058
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5509
Gene Expression Omnibus
Liver response to various toxins
35
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