Liver response to various toxins
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE5509
TitleLiver response to various toxins
DescriptionAnalysis of livers of animals 48 hours after exposure to the toxin alpha-naphthylisothiocyanate (ANIT), dimethylnitrosamine (DMN), or n-methylformamide (NMF). Results provide insight into the mechanism of toxicity of each compound.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5509
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Drug Name
Geneset

Small molecules which mimic Caerulein treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Caerulein treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic Rosiglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Rosiglitazone treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic 1-naphthyl isothiocyanate treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse 1-naphthyl isothiocyanate treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic N-nitrosodimethylamine treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse N-nitrosodimethylamine treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic N-methylformamide treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse N-methylformamide treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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