Small molecules which reverse 1-naphthyl isothiocyanate treatment
Canned Analysis
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General Information
AccessionDCA00013327
TitleSmall molecules which reverse 1-naphthyl isothiocyanate treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by 1-naphthyl isothiocyanate treatment in the Livers - 48 hours after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6c2e467bea600fb8f92
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3568
Cell TypeLivers - 48 hours after exposure
Drug Name1-naphthyl isothiocyanate
Organismrat
PubChem CID11080
SMILES IDC1=CC=C2C(=C1)C=CC=C2N=C=S
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM127079, GSM127080, GSM127081, GSM127082, GSM127083, GSM127084, GSM127085, GSM127086, GSM127087
Perturbed SamplesGSM127049, GSM127050, GSM127051, GSM127052, GSM127053
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5509
Gene Expression Omnibus
Liver response to various toxins
35
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