Small molecules which mimic N-nitrosodimethylamine treatment
Canned Analysis
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General Information
AccessionDCA00013328
TitleSmall molecules which mimic N-nitrosodimethylamine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by N-nitrosodimethylamine treatment in the Livers - 48 hours after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6b6e467bea600fb8f8c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3569
Cell TypeLivers - 48 hours after exposure
Drug NameN-nitrosodimethylamine
Organismrat
PubChem CID6124
SMILES IDCN(C)N=O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM127079, GSM127080, GSM127081, GSM127082, GSM127083, GSM127084, GSM127085, GSM127086, GSM127087
Perturbed SamplesGSM127059, GSM127060, GSM127061, GSM127062, GSM127063
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5509
Gene Expression Omnibus
Liver response to various toxins
35
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