Small molecules which reverse N-nitrosodimethylamine treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013329
TitleSmall molecules which reverse N-nitrosodimethylamine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by N-nitrosodimethylamine treatment in the Livers - 48 hours after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6b8e467bea600fb8f8e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3569
Cell TypeLivers - 48 hours after exposure
Drug NameN-nitrosodimethylamine
Organismrat
PubChem CID6124
SMILES IDCN(C)N=O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM127079, GSM127080, GSM127081, GSM127082, GSM127083, GSM127084, GSM127085, GSM127086, GSM127087
Perturbed SamplesGSM127059, GSM127060, GSM127061, GSM127062, GSM127063
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5509
Gene Expression Omnibus
Liver response to various toxins
35
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.