Small molecules which mimic 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013528
TitleSmall molecules which mimic 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment in the epithelial lung cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d335e467bea600fb8e00
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3682
Cell Typeepithelial lung cells
Drug Name2,3-dimethoxy-1,4-naphtoquinone (dmnq)
Organismhuman
PubChem CID3136
SMILES IDCOC1=C(C(=O)C2=CC=CC=C2C1=O)OC
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM980291, GSM980292, GSM980293
Perturbed SamplesGSM980294, GSM980295, GSM980296
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39843
Gene Expression Omnibus
Expression data of cystic fibrosis and non-cystic fibrosis airway cell lines under oxidative stress
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.