Expression data of cystic fibrosis and non-cystic fibrosis airway cell lines under oxidative stress
Transcriptomics Dataset
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General Information
AccessionGSE39843
TitleExpression data of cystic fibrosis and non-cystic fibrosis airway cell lines under oxidative stress
DescriptionCF's physiopathology is poorly explained by the mutation alone. The oxydative stress could be a major factor of this illness . Study its impact on transcriptome's CF cell line could be ameliorate our understanding of the evolution of cystic fibrosis. we used microarray technology to evaluate under oxydative stress, the transcriptional state of an epithelial lung cell issued from a human with cystic fibrosis and to identify a set of modulated genes associated to survival cell processes.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39843
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Geneset

Small molecules which mimic 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated following 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated following 2,3-dimethoxy-1,4-naphtoquinone (dmnq) treatment
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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