Enrichment analysis of genes dysregulated following Doxorubicin treatment
Canned Analysis
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General Information
AccessionDCA00013806
TitleEnrichment analysis of genes dysregulated following Doxorubicin treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Doxorubicin treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088041
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2721
Drug NameDoxorubicin
DrugBank IDDB00997
Organismhuman
PubChem CID31703
SMILES IDCC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
Characteristic Direction parameters
Control SamplesGSM11707, GSM11716
Perturbed SamplesGSM11694, GSM11695
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE763
Gene Expression Omnibus
Breast cancer cell line ZR-75-1 response to chemotherapeutics: time course
28
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