Enrichment analysis of genes dysregulated following Angiotensin ii treatment
Canned Analysis
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General Information
AccessionDCA00014038
TitleEnrichment analysis of genes dysregulated following Angiotensin ii treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Angiotensin ii treated cells and untreated control cells in the Heart (PKCζ - Knockout) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089411
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3217
Cell TypeHeart (PKCζ - Knockout)
Drug NameAngiotensin ii
Organismmouse
PubChem CID172198
SMILES IDCCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
Characteristic Direction parameters
Control SamplesGSM721519, GSM721520, GSM721521
Perturbed SamplesGSM721517, GSM721518
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE29145
Gene Expression Omnibus
Protein kinase C (PKC) knockout response to chronic angiotensin treatment in vivo: heart
38
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