Enrichment analysis of genes dysregulated following Cyclophosphamide treatment
Canned Analysis
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General Information
AccessionDCA00014369
TitleEnrichment analysis of genes dysregulated following Cyclophosphamide treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Cyclophosphamide treated cells and untreated control cells in the Pancreatic islets (from BDC2.5/NOD transgenics) - 200 mg/kg - 3 Day after treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089518
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3628
Cell TypePancreatic islets (from BDC2.5/NOD transgenics) - 200 mg/kg - 3 Day after treatment
Drug NameCyclophosphamide
DrugBank IDDB00531
Organismmouse
PubChem CID2907
SMILES IDC1CNP(=O)(OC1)N(CCCl)CCCl
Characteristic Direction parameters
Control SamplesGSM41439, GSM41440, GSM41441, GSM41442, GSM41443, GSM41444, GSM41445, GSM41446
Perturbed SamplesGSM41454, GSM41455, GSM41456
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2254
Gene Expression Omnibus
Type 1 diabetes model response to cyclophosphamide: time course
28
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