Small molecules which mimic PRKCZ KO
Canned Analysis
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General Information
AccessionDCA00019827
TitleSmall molecules which mimic PRKCZ KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PRKCZ KO in the Heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22c8ce467bea600fbb4e4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:1093
Cell TypeHeart
Gene Symbol (human)PRKCZ
Gene Symbol (mouse)Prkcz
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM721522, GSM721523, GSM721524
Perturbed SamplesGSM721517, GSM721518
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29145
Gene Expression Omnibus
Protein kinase C (PKC) knockout response to chronic angiotensin treatment in vivo: heart
38
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