Small molecules which mimic CLDN16 Deficiency
Canned Analysis
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General Information
AccessionDCA00019985
TitleSmall molecules which mimic CLDN16 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CLDN16 Deficiency in the Kidneys - Homozygous null cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21b48e467bea600fbad78
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:1177
Cell TypeKidneys - Homozygous null
Gene Symbol (human)CLDN16
Gene Symbol (mouse)Cldn16
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM498687, GSM498688, GSM498689, GSM498690
Perturbed SamplesGSM498694, GSM498695, GSM498696, GSM498697
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19961
Gene Expression Omnibus
Claudin16 deficiency effect on kidneys
14
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