Small molecules which mimic LMNA KO
Canned Analysis
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General Information
AccessionDCA00020029
TitleSmall molecules which mimic LMNA KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LMNA KO in the Gastrocnemius muscles (untreated) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23ad9e467bea600fbbb2c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgamalloponte
CREEDS IDgene:1203
Cell TypeGastrocnemius muscles (untreated)
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM100719, GSM119594
Perturbed SamplesGSM119600, GSM119605, GSM119609
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5304
Gene Expression Omnibus
Emery-Dreifuss muscular dystrophy model: regenerating skeletal muscle
42
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