Emery-Dreifuss muscular dystrophy model: regenerating skeletal muscle
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE5304
TitleEmery-Dreifuss muscular dystrophy model: regenerating skeletal muscle
DescriptionAnalysis of regenerating gastrocnemius muscles of emerin and lamin A/C knockout mutants at various time points up to 4 days following treatment with cardiotoxin to induce muscle injury. Mutations in emerin and lamin A/C cause Emery-Dreifuss muscular dystrophy (EDMD).
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5304
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Hs Gene Symbol
Mm Gene Symbol
Geneset

Small molecules which mimic EMD KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse EMD KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic EMD KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse EMD KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic EMD KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse EMD KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic LMNA KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMNA KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic LMNA KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse LMNA KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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