Small molecules which reverse CDH1 OE
Canned Analysis
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General Information
AccessionDCA00020102
TitleSmall molecules which reverse CDH1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CDH1 OE in the cell line: Mkn28 cell type: human gastric tubular adenocarcinoma tissue origin: stomach (70 year-old female) overexpressing canonical CDH1 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21090e467bea600fba8ca
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2350
Cell Typecell line: Mkn28 cell type: human gastric tubular adenocarcinoma tissue origin: stomach (70 year-old female) overexpressing canonical CDH1
Gene Symbol (human)CDH1
Gene Symbol (mouse)Cdh1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM806616, GSM806617, GSM806618
Perturbed SamplesGSM806619, GSM806620, GSM806621
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32540
Gene Expression Omnibus
E-cadherin/CDH1 intron2 protein isoform overexpression in Mkn28 gastric tubular adenocarcinoma cell line
33
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