E-cadherin/CDH1 intron2 protein isoform overexpression in Mkn28 gastric tubular adenocarcinoma cell line
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE32540
TitleE-cadherin/CDH1 intron2 protein isoform overexpression in Mkn28 gastric tubular adenocarcinoma cell line
DescriptionAnalysis of MKN28 cell line (E-cadherin positive) overexpressing E-cadherin isoform CDH1a. CDH1a overexpression promotes mild MKN28 aggregation and increases invasion. Results provide insight into role of CDH1a as a negative modulator of canonical E-cadherin function in cancer cells.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE32540
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Hs Gene Symbol
Mm Gene Symbol
Geneset

Small molecules which mimic CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse CDH1 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic PCDH12 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse PCDH12 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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