Small molecules which reverse ZXDC Depletion (with phorbol 12-myristate 13-acetate agent treatment)
Canned Analysis
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General Information
AccessionDCA00020154
TitleSmall molecules which reverse ZXDC Depletion (with phorbol 12-myristate 13-acetate agent treatment)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ZXDC Depletion (with phorbol 12-myristate 13-acetate agent treatment) in the U937 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d208cee467bea600fba55a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:1257
Cell TypeU937
Gene Symbol (human)ZXDC
Gene Symbol (mouse)Zxdc
Organismmouse
Perturbation TypeDepletion (with phorbol 12-myristate 13-acetate agent treatment)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1103975, GSM1103979, GSM1103983
Perturbed SamplesGSM1103976, GSM1103980, GSM1103984
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45417
Gene Expression Omnibus
Zinc finger transcription factor ZXDC depletion effect on myeloid cell line undergoing differentiation
35
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