Zinc finger transcription factor ZXDC depletion effect on myeloid cell line undergoing differentiation
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE45417
TitleZinc finger transcription factor ZXDC depletion effect on myeloid cell line undergoing differentiation
DescriptionAnalysis of U937 myeloid cells treated with phorbol 12-myristate 13-acetate (PMA) and depleted for the zinc finger transcription factor ZXDC. PMA treatment induces myeloid cell differentiation. Results provide insight into the role of ZXDC in myeloid cell differentiation.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE45417
RepositoryGene Expression Omnibus
Tools used to analyze the dataset
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset
Filters  
Dataset Accession
Tool Name
Organism
Direction
Cell Type
Pert Type
Geneset
Small molecules which mimic Phorbol 12-myristate 13-acetate (pma) treatment
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse Phorbol 12-myristate 13-acetate (pma) treatment
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated following Phorbol 12-myristate 13-acetate (pma) treatment
PAEA, Characteristic Direction
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Small molecules which mimic ZXDC Depletion (with phorbol 12-myristate 13-acetate agent treatment)
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse ZXDC Depletion (with phorbol 12-myristate 13-acetate agent treatment)
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic ZXDC depletion (treatment with phorbol 12-myristate 13-acetate)
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse ZXDC depletion (treatment with phorbol 12-myristate 13-acetate)
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic ZXDC KD
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse ZXDC KD
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic ZXDC KD
L1000CDS2, Characteristic Direction
The L1000 database was queried in order to identify small molecule perturbations which mim...
...
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