Small molecules which mimic ZXDC depletion (treatment with phorbol 12-myristate 13-acetate)
Canned Analysis
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General Information
AccessionDCA00020155
TitleSmall molecules which mimic ZXDC depletion (treatment with phorbol 12-myristate 13-acetate)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ZXDC depletion (treatment with phorbol 12-myristate 13-acetate) in the myeloid cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d202c3e467bea600fba2b4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:3044
Cell Typemyeloid
Gene Symbol (human)ZXDC
Gene Symbol (mouse)Zxdc
Organismhuman
Perturbation Typedepletion (treatment with phorbol 12-myristate 13-acetate)
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1103976, GSM1103980, GSM1103984
Perturbed SamplesGSM1103973, GSM1103977, GSM1103981
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE45417
Gene Expression Omnibus
Zinc finger transcription factor ZXDC depletion effect on myeloid cell line undergoing differentiation
35
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