Small molecules which reverse NFE2L2 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020166
TitleSmall molecules which reverse NFE2L2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NFE2L2 KO in the lung 5 month medium smoke exposure 1 day recovery cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f762e467bea600fb9df0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:1260
Cell Typelung 5 month medium smoke exposure 1 day recovery
Gene Symbol (human)NFE2L2
Gene Symbol (mouse)Nfe2l2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM457975, GSM457976, GSM457977, GSM457978
Perturbed SamplesGSM457991, GSM457992, GSM457993, GSM457994
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE18344
Gene Expression Omnibus
Nrf2-deficient lung response to cigarette smoke: dose response and time course
98
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.