Small molecules which mimic SNCA SNCA triplication
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00020223
TitleSmall molecules which mimic SNCA SNCA triplication
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SNCA SNCA triplication in the iPSC cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20e62e467bea600fba7d4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:1286
Cell TypeiPSC
Gene Symbol (human)SNCA
Gene Symbol (mouse)Snca
Organismhuman
Perturbation TypeSNCA triplication
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM763976, GSM763977
Perturbed SamplesGSM763978, GSM763979
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE30792
Gene Expression Omnibus
Parkinson's disease induced pluripotent stem cell model with triplication of the -synuclein locus
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.