Small molecules which reverse MYC KD
Canned Analysis
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General Information
AccessionDCA00020384
TitleSmall molecules which reverse MYC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYC KD in the MDA-MB-231 BREAST CANCER cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20f57e467bea600fba842
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:140
Cell TypeMDA-MB-231 BREAST CANCER cell line
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM136095, GSM136097
Perturbed SamplesGSM136090, GSM136092
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5823
Gene Expression Omnibus
c-MYC depletion effect on carcinoma cell lines
63
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