c-MYC depletion effect on carcinoma cell lines
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE5823
Titlec-MYC depletion effect on carcinoma cell lines
DescriptionAnalysis of breast and cervix carcinoma cell lines depleted for c-MYC by siRNA knockdown. Abnormal activation of c-MYC contributes to breast and cervix carcinogenesis. Results provide insight into the molecular basis of the developmental and oncogenic roles of MYC proteins.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5823
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic MYC KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYC KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYC KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYC KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYC KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYC KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYC KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYC KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYC KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYC KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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