Small molecules which mimic MYC KD
Canned Analysis
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General Information
AccessionDCA00020385
TitleSmall molecules which mimic MYC KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by MYC KD in the cancer_cell_lines cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c97e467bea600fbade0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorKevin
CREEDS IDgene:2075
Cell Typecancer_cell_lines
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM136079, GSM136081, GSM136083, GSM136085, GSM136087, GSM136089, GSM136091, GSM136095, GSM136097
Perturbed SamplesGSM136080, GSM136082, GSM136084, GSM136086, GSM136088, GSM136090, GSM136092, GSM136096, GSM136098
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5823
Gene Expression Omnibus
c-MYC depletion effect on carcinoma cell lines
63
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