Small molecules which mimic POU5F1 OE
Canned Analysis
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General Information
AccessionDCA00020483
TitleSmall molecules which mimic POU5F1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by POU5F1 OE in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2304de467bea600fbb68c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1423
Cell TypeES cells
Gene Symbol (human)POU5F1
Gene Symbol (mouse)Pou5f1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM857505, GSM857506
Perturbed SamplesGSM857511, GSM857512
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34920
Gene Expression Omnibus
NANOG-OCT4-SOX2 Regulatory Module in Human Embryonic Stem Cells (dataset 4)
21
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