Small molecules which reverse NFKB1 KD
Canned Analysis
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General Information
AccessionDCA00020732
TitleSmall molecules which reverse NFKB1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NFKB1 KD in the U-87 MG glioma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22fcae467bea600fbb652
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1558
Cell TypeU-87 MG glioma cells
Gene Symbol (human)NFKB1
Gene Symbol (mouse)Nfkb1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1593737, GSM1593738, GSM1593739
Perturbed SamplesGSM1593731, GSM1593732, GSM1593733
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE65363
Gene Expression Omnibus
Expression data from U-87 human glioma cells with proficient and deficient NF-B after treatment with temozolomide
7
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