Small molecules which reverse PAFAH1B1 KO
Canned Analysis
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General Information
AccessionDCA00020756
TitleSmall molecules which reverse PAFAH1B1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PAFAH1B1 KO in the brain (Embryonic day 14) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22524e467bea600fbb19a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1613
Cell Typebrain (Embryonic day 14)
Gene Symbol (human)PAFAH1B1
Gene Symbol (mouse)Pafah1b1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM866834, GSM866835, GSM866836, GSM866846, GSM866847, GSM866848
Perturbed SamplesGSM866852, GSM866853, GSM866854
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35366
Gene Expression Omnibus
Models of Neuronal Migration Defects: time course
112
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