Models of Neuronal Migration Defects: time course
Transcriptomics Dataset
FAIR Metrics
0 evaluations
General Information
AccessionGSE35366
TitleModels of Neuronal Migration Defects: time course
DescriptionAnalysis of brains from 4 models of human neuronal migration defects (Lis1, Dcx, Ywhae, Ndel) at 3 developmental stages. Neuronal migration defects (NMDs) are an important cause of severe epilepsy and mental retardation. Results provide insight into molecular mechanisms underlying the NMDs.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE35366
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Hs Gene Symbol
Pert Type
Mm Gene Symbol
Geneset

Small molecules which mimic YWHAE KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse YWHAE KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic PAFAH1B1 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse PAFAH1B1 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic DCX KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse DCX KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic PAFAH1B1 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse PAFAH1B1 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic NDEL1 KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NDEL1 KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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