Small molecules which reverse MYB KD
Canned Analysis
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General Information
AccessionDCA00021222
TitleSmall molecules which reverse MYB KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYB KD in the cell line: prostate cancer cell line PC-3M cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d239bee467bea600fbbab2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1842
Cell Typecell line: prostate cancer cell line PC-3M
Gene Symbol (human)MYB
Gene Symbol (mouse)Myb
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1196816, GSM1196824, GSM1196832
Perturbed SamplesGSM1196817, GSM1196825, GSM1196833
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49286
Gene Expression Omnibus
Genome-wide analysis of c-Myb-responsive gene expression in prostate cancer cells
28
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