Genome-wide analysis of c-Myb-responsive gene expression in prostate cancer cells
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE49286
TitleGenome-wide analysis of c-Myb-responsive gene expression in prostate cancer cells
DescriptionAnalysis of c-Myb-regulation of gene expression. The hypothesis tested in the present study was that c-Myb influences the expression of specific sets of genes that are involved in cell cycle, DNA replication, recombination and repair. Results provide important information on c-Myb-responsive genes that may be crucial to the cell survival and the progression of prostate cancer.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49286
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Small molecules which mimic MYB KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYB KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYB KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYB KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYB KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYB KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic MYB KD
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse MYB KD
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in MYB KD
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in MYB KD
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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