Small molecules which reverse ERBB3 drugactivation
Canned Analysis
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General Information
AccessionDCA00021308
TitleSmall molecules which reverse ERBB3 drugactivation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ERBB3 drugactivation in the melanocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22a29e467bea600fbb3d6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1899
Cell Typemelanocytes
Gene Symbol (human)ERBB3
Gene Symbol (mouse)Erbb3
Organismmouse
Perturbation Typedrugactivation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM536238, GSM536239, GSM536240
Perturbed SamplesGSM536235, GSM536236, GSM536237
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21463
Gene Expression Omnibus
NRG1/ERBB3 signaling in melanocyte Melan-Ink4a cells
7
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