Small molecules which reverse MAP3K7 knockout
Canned Analysis
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General Information
AccessionDCA00021560
TitleSmall molecules which reverse MAP3K7 knockout
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAP3K7 knockout in the dendritic cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d227d0e467bea600fbb2ca
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2057
Cell Typedendritic cells
Gene Symbol (human)MAP3K7
Organismmouse
Perturbation Typeknockout
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM848777, GSM848778, GSM848779
Perturbed SamplesGSM848780, GSM848781, GSM848782
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34417
Gene Expression Omnibus
TAK1-dependent checkpoint in dendritic cell survival regulates immune homeostasis and function
7
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