Small molecules which reverse SP1 KD
Canned Analysis
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General Information
AccessionDCA00021720
TitleSmall molecules which reverse SP1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SP1 KD in the cell line: HeLa cell type: human Cervical Carcinoma genotype/variation: parental cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d95e467bea600fbae4e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2219
Cell Typecell line: HeLa cell type: human Cervical Carcinoma genotype/variation: parental
Gene Symbol (human)SP1
Gene Symbol (mouse)Sp1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM930228, GSM930229, GSM930230
Perturbed SamplesGSM930231, GSM930232, GSM930233
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37935
Gene Expression Omnibus
Identification of Sp1 targets involved in proliferation and cancer
7
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