Small molecules which reverse SYK Depletion
Canned Analysis
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General Information
AccessionDCA00021990
TitleSmall molecules which reverse SYK Depletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SYK Depletion in the MCF10A breast epithelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c47e467bea600fbadbe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorames88cav
CREEDS IDgene:2857
Cell TypeMCF10A breast epithelial cells
Gene Symbol (human)SYK
Gene Symbol (mouse)Syk
Organismhuman
Perturbation TypeDepletion
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM406560, GSM406562, GSM406563, GSM406565
Perturbed SamplesGSM406566, GSM406567, GSM406570, GSM406571
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16200
Gene Expression Omnibus
Syk depletion effect on breast epithelial cell line
33
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